Dr. Iafe is a tenured Associate Professor and current Chair of the Department of Chemistry & Biochemistry at California State University San Marcos (ÌÇÐÄÉÙÅ®). He earned his B.S. in Chemistry, graduating cum laude with Honors from Loyola Marymount University, where he conducted undergraduate research with Dr. James Roe and Dr. James Landry. He went on to complete his M.S. in Computational Chemistry under the mentorship of Dr. Kendall N. Houk and his Ph.D. in Chemistry with Dr. Craig Merlic at the University of California, Los Angeles (UCLA).
Following his doctoral studies, Dr. Iafe served as a Visiting Assistant Professor at the W.M. Keck Science Department of the Claremont Colleges and conducted postdoctoral research with Prof. Anna Wenzel. He joined ÌÇÐÄÉÙÅ® in 2014 and was awarded tenure and promoted to Associate Professor in 2020.
Dr. Iafe’s research focuses on organic chemistry, with an emphasis on method development and small molecule synthesis. In addition to his research and leadership roles, he teaches a range of undergraduate and graduate courses in organic chemistry, including CHEM 200, 201, 201L, 202, 202L, and 502.
- Chair, Department of Chemistry & Biochemistry
- CB-TLC Program Director –
- VMLC Program Director –
- Faculty Champion for Teacher Recruitment (FaCTR) Fellow
- Committees: FDC, CUGR, Reinstatement
- Campus Representative:
- Sigma Xi ÌÇÐÄÉÙÅ® Chapter President
Publications (* denotes undergraduate student)
- *Seranno, A.; Kuo, J. L.; Boon, B. A.; Merlic, C. A.; Iafe, R. G. "" Tetrahedron Lett. 2026, 180, 156055.
- *King, B. H.; *Wang, M. L.; *Jesse, K. A.; *Kaur, G.; *Tran, B.; *Walser-Kuntz, R.; Iafe, R. G.; Wenzel, A. G. "." J. Org. Chem. 2020, 85, 13256–13263.
- *Oakley, J. V.; *Stanley, T. J.; *Jesse, K. A.; *Melanese, A. K; *Alvarez, A. A.; Prince, A. L.; Cain, S. E.; Wenzel, A. G.; Iafe, R. G. "" Euro. J. Org. Chem. 2019, 42, 7063–7066.
- Karabiyikoglu, S.; Iafe, R. G.; Merlic, C. A. "" Org. Lett. 2015, 17, 5248–5251.
- *Vinson, A. R. S.; *Davis, V. K.; *Arunasalam, A.; *Jesse, K. A.; *Hamilton, R. E.; *Shattuck, M. A.; *Hu, A. C.; Iafe, R. G.; Wenzel, A. G. "" Synlett 2015, 26, 765–770.
- Iafe, R. G.; *Kuo, J. L.; Hochstatter, D. G.; *Saga, T.; *Turner, J. W.; Merlic, C. A. "" Org. Lett. 2013, 15, 582–585.
- Iafe, R. G.; Chan, D. G.; *Kuo, J. L.; Boon, B. A.; *Faizi, D. J.; Saga, T.; *Turner, J. W.; Merlic, C. A. "" Org. Lett. 2012, 14, 4282–4285.
- Gutierrez, O.; Iafe, R. G.; Houk, K. N. "" Org. Lett. 2009, 11, 4298–4301.
- Ess, D. H.; Wheeler, S. E.; Iafe, R. G.; Xu, L.; Celebi-Olcum, N.; Houk, K. N. "" Angew. Chem. Int. Ed. 2008, 47, 7592–7601.
- Iafe, R. G.; Houk, K. N. "" J. Org. Chem. 2008, 73, 2679–2686.
- Iafe, R. G.; Houk, K. N. "" Org. Lett. 2006, 8, 3469–3472.
Grants/Fellowships
- 2025:
- 2025: RSCA Cottrell Lectureships Award $1,500
- 2024: CSUBIOTECH Faculty-Graduate Student Research Collaboration Grant $7,500
- 2023: Beyond Benign Green Chemistry Education Challenge Award $10,000
- 2023: ÌÇÐÄÉÙÅ® CALM $4,000
- 2023: CSUPERB CD $15,000
- 2023: Pfizer AIR Diversity (Llamas) $20,000
- 2020:
- 2020: CSUPERB Presidents' Commission Scholarship (Stockton) $8,000
- 2019: Hamilton $1,000
- 2019: CSUPERB Presidents' Commission Scholarship (Shoemaker) $8,000
- 2019: ACS DOC SURF (Melanese) $5,000
- 2018: FC PD Grant $800
- 2018: OGSR GPSM $1,732
- 2018: NCHEA *NSPIRE Graduate Student Lecture Series $3,000
- 2018: Jean Dreyfus Lectureship for Undergraduate Institutions $18,500
- 2018: OGSR GPSM $3,000
- 2017: CALM $1,000
- 2017: CSUPERB Presidents' Commission Scholarship (Apolinar) $8,000
- 2015. OGSR GPSM $3,000
- 2015. CSUPERB NI $15,000
- CHEM 200: Bridge to Organic Chemistry
- CHEM 201: Organic Chemistry I
- CHEM 201L: Organic Chemistry I Lab
- CHEM 202: Organic Chemsitry II
- CHEM 202L: Organic Chemistry II Lab
- Chem 399: Special Problems in Chemistry - Laboratory
- CHEM 499: Senior Laboratory Thesis and Seminar
- CHEM 502: Advanced Organic Synthesis
- CHEM 691: Graduate Student Colloquium in Chemistry and Biochemistry
- CHEM 697: Directed Studies
- CHEM 698: Thesis Research
*To enroll in CHEM 399/CHEM 499, refer to the Department's research web page. CHEM 697/CHEM 698 is restricted to Chemistry MS students. Prospective undergraduate and M.S. researchers are encouraged to contact Prof. Iafe at riafe(at)csusm.edu. Prospective M.S. students should apply to the graduate program at ÌÇÐÄÉÙÅ®. Individuals seeking to join the Iafe lab should expect to undergo a rigorous selection process that includes submission of relevant application materials and an in-person interview.
Follow the Team — —
Undergraduate Students
Kiera Ramirez
Major: Biochemistry
After my undergraduate studies I plan to pursue a PhD in chemistry, focusing on organic synthesis and chemical biology. I see myself working in drug discovery research, contributing to teams that turn fundamental chemistry into real medicines that make a difference.
Arianna Serrano
Summer Scholar, Bridges Scholar
Major: Chemistry
After undergraduate school, I plan to go to graduate school to get a Ph.D. In chemistry to work in the field of pharmaceutical research. My hobbies include hiking, photography, and traveling.
Group Photos:

Thank you to the following for providing financial assistance to our lab: ÌÇÐÄÉÙÅ®, NSF, Beckman Foundation, Dreyfus Foundation, Goldwater, Pfizer, Hologic, ACS Division of Organic Chemistry, Genentech, McNair, CTREE, U-Rise, NCHEA, ÌÇÐÄÉÙÅ® OGSR, Hamilton, San Diego Foundation, and CSUPERB.